Special Issue 3: Personalized (N-of-1) Trials

From the Editors

Introducing Data Sciences to N-of-1 Designs, Statistics, Use-Cases, the Future, and the Moniker ‘N-of-1’ Trial

by Karina Davidson, Ken Cheung, Ciaran Friel, and Jerry Suls

Published: Sep 08, 2022

Special Issue 3: Personalized (N-of-1) Trials: Methods, Applications, and Impact

The Family of Single-Case Experimental Designs

by Leonard H. Epstein and Jesse Dallery

Published: Sep 08, 2022

Evaluating Personalized (N-of-1) Trials in Rare Diseases: How Much Experimentation Is Enough?

by Ken Cheung and Hiroshi Mitsumoto

Published: Sep 08, 2022

Personalized Data Science and Personalized (N-of-1) Trials: Promising Paradigms for Individualized Health Care

by Naihua Duan, Daniel Norman, Christopher Schmid, Ida Sim, and Richard L. Kravitz

Published: Sep 08, 2022

Accommodating Serial Correlation and Sequential Design Elements in Personalized Studies and Aggregated Personalized Studies

by Nicholas Schork

Published: Sep 08, 2022

Bayesian Models for N-of-1 Trials

by Christopher Schmid and Jiabei Yang

Published: Sep 08, 2022

An R Shiny App for a Chronic Lower Back Pain Study, Personalized N-of-1 Trial

by Thevaa Chandereng

Published: Sep 08, 2022

Quantitative Synthesis of Personalized Trials Studies: Meta-Analysis of Aggregated Data Versus Individual Patient Data

by Mariola Moeyaert and Joelle Fingerhut

Published: Sep 08, 2022

N-of-1 Trials, Their Reporting Guidelines, and the Advancement of Open Science Principles

by Antony Porcino and Sunita Vohra

Published: Sep 08, 2022

Personalized Trial Ethics and Institutional Review Board Submissions

by Joyce P. Samuel and Susan H. Wootton

Published: Sep 08, 2022

Conduct and Implementation of Personalized Trials in Research and Practice

by Richard L. Kravitz and Naihua Duan

Published: Sep 08, 2022

Personalized Feedback for Personalized Trials: Construction of Summary Reports for Participants in a Series of Personalized Trials for Chronic Lower Back Pain

by Stefani D'Angelo, Heejoon Ahn, Danielle Miller, Rachel Monane, and Mark Butler

Published: Sep 08, 2022

Use Cases

Why Do I Get Side Effects? Personalized (N-of-1) Trials for Statin Intolerance and the Nocebo Effect

by James Philip Howard, Frances A. Wood, and Darrel P. Francis

Published: Sep 08, 2022

A Series of Virtual Interventions for Chronic Lower Back Pain: A Feasibility Pilot Study for a Series of Personalized (N-of-1) Trials

by Mark Butler, Stefani D'Angelo, Melissa Kaplan, Zarrin Tashnim, Danielle Miller, Heejoon Ahn, Louise Falzon, Andrew J. Dominello, and 4 more

Published: Sep 08, 2022

Personalized (N-of-1) Trials for Patient-Centered Treatments of Multimorbidity

by Jerry Suls, Catherine Alfano, and Christina Yap

Published: Sep 08, 2022

Personalized (N-of-1) Trials: Methods, Applications, and Impact

Special Issue 3

From the Editors

Introducing Data Sciences to N-of-1 Designs, Statistics, Use-Cases, the Future, and the Moniker ‘N-of-1’ Trial

Contents

The Family of Single-Case Experimental Designs

Evaluating Personalized (N-of-1) Trials in Rare Diseases: How Much Experimentation Is Enough?

Personalized Data Science and Personalized (N-of-1) Trials: Promising Paradigms for Individualized Health Care

Accommodating Serial Correlation and Sequential Design Elements in Personalized Studies and Aggregated Personalized Studies

Bayesian Models for N-of-1 Trials

An R Shiny App for a Chronic Lower Back Pain Study, Personalized N-of-1 Trial

Quantitative Synthesis of Personalized Trials Studies: Meta-Analysis of Aggregated Data Versus Individual Patient Data

N-of-1 Trials, Their Reporting Guidelines, and the Advancement of Open Science Principles

Personalized Trial Ethics and Institutional Review Board Submissions

Conduct and Implementation of Personalized Trials in Research and Practice

Personalized Feedback for Personalized Trials: Construction of Summary Reports for Participants in a Series of Personalized Trials for Chronic Lower Back Pain

Use Cases

Why Do I Get Side Effects? Personalized (N-of-1) Trials for Statin Intolerance and the Nocebo Effect

A Series of Virtual Interventions for Chronic Lower Back Pain: A Feasibility Pilot Study for a Series of Personalized (N-of-1) Trials

Personalized (N-of-1) Trials for Patient-Centered Treatments of Multimorbidity