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Medications and Suicide: High Dimensional Empirical Bayes Screening (iDEAS): Supplementary File

Published onNov 01, 2019
Medications and Suicide: High Dimensional Empirical Bayes Screening (iDEAS): Supplementary File
·
key-enterThis Pub is a Supplement to

All 922 Medications Included in the Analysis

# of Suicide Attempts

Drug

OR (95% CIs)

Pre

Post

# of Subjects

APAP/Butalbital/Caff/Codeine Phos

1.07 (0.52-2.20)

17

29

89,060

APAP/Dichloralphenazone/Isometheptene Mucate

1.10 (0.62-1.95)

54

69

407,602

Abacavir Sulfate

1.04 (0.37-2.92)

0

1

6,982

Abacavir Sulfate/Lamivudine

0.83 (0.34-2.04)

4

2

13,536

Acamprosate Calcium

0.51 (0.34-0.76)

238

124

53,166

Acarbose

1.06 (0.42-2.66)

1

4

26,383

Acebutolol Hydrochloride

1.18 (0.44-3.20)

0

1

21,944

Acetaminophen

1.05 (0.39-2.80)

0

2

11,062

Acetaminophen/Butalbital

0.95 (0.44-2.04)

15

16

104,322

Acetaminophen/Butalbital/Caffeine

1.68 (1.16-2.44)

147

288

1,154,666

Acetaminophen/Codeine Phosphate

1.25 (0.97-1.62)

395

515

5,451,457

Acetaminophen/Hydrocodone Bitartrate

1.31 (1.16-1.47)

1,994

2,674

23,014,316

Acetaminophen/Oxycodone Hydrochloride

1.09 (0.92-1.30)

954

1,071

8,001,490

Acetaminophen/Tramadol Hydrochloride

1.09 (0.67-1.76)

93

109

902,127

Acetazolamide

1.14 (0.49-2.62)

7

9

176,175

Acetic Acid

1.12 (0.44-2.86)

2

1

51,169

Acetic Acid/Hydrocortisone

1.12 (0.47-2.62)

6

6

153,446

Acitretin

1.15 (0.42-3.14)

0

1

17,922

Aclidinium Bromide

0.98 (0.37-2.60)

1

1

10,129

Acrivastine/Pseudoephedrine Hydrochloride

1.07 (0.42-2.77)

1

2

24,999

Acyclovir

1.16 (0.79-1.71)

166

204

2,243,625

Acyclovir/Hydrocortisone

1.10 (0.40-3.03)

0

1

11,677

Adalimumab

1.18 (0.52-2.66)

7

14

146,357

Adapalene

1.25 (0.75-2.09)

72

103

931,135

Adapalene/Benzoyl Peroxide

1.04 (0.60-1.81)

63

73

456,508

Al Hydroxide/Mg Hydroxide/Simethicone;Diphenhydram

0.94 (0.41-2.18)

7

8

49,536

Albendazole

1.17 (0.46-3.03)

0

3

32,083

Albuterol Sulfate

1.12 (0.92-1.36)

770

887

10,270,030

Albuterol Sulfate/Ipratropium Bromide

0.99 (0.58-1.69)

73

76

615,597

Alcaftadine

1.14 (0.44-2.96)

2

0

53,176

Alclometasone Dipropionate

1.19 (0.51-2.81)

5

7

178,695

Alendronate Sodium

1.16 (0.56-2.42)

20

21

808,379

Alfuzosin Hydrochloride

1.38 (0.55-3.49)

0

4

112,921

Aliskiren

1.09 (0.45-2.66)

3

4

64,005

Aliskiren/Hydrochlorothiazide

1.10 (0.41-2.96)

1

0

19,418

Allopurinol

1.33 (0.66-2.70)

20

33

775,032

Almotriptan Malate

1.08 (0.47-2.47)

6

13

69,800

Alosetron Hydrochloride

0.87 (0.33-2.25)

2

1

7,562

Alprazolam

1.72 (1.47-2.01)

1,035

1,861

4,719,202

Alprostadil

1.10 (0.43-2.78)

1

3

31,423

Aluminum Chloride

0.92 (0.48-1.77)

38

33

378,313

Amantadine Hydrochloride

0.74 (0.38-1.43)

43

26

197,723

Ambrisentan

0.93 (0.32-2.73)

0

1

1,864

Amiloride Hydrochloride

0.84 (0.34-2.04)

4

3

14,331

Amiodarone Hydrochloride

0.91 (0.41-2.03)

13

8

127,990

Amitriptyline Hydrochloride

1.23 (0.93-1.63)

323

425

1,412,911

Amitriptyline Hydrochloride/Chlordiazepoxide

1.07 (0.40-2.86)

0

2

13,339

Amitriptyline Hydrochloride/Perphenazine

0.72 (0.31-1.67)

8

7

10,341

Amlodipine Besylate

0.61 (0.43-0.85)

324

185

2,694,151

Amlodipine Besylate/Atorvastatin Calcium

1.25 (0.50-3.14)

2

2

116,336

Amlodipine Besylate/Benazepril Hydrochloride

1.39 (0.66-2.90)

15

28

735,989

Amlodipine Besylate/HCTZ/Olmesartan Medoxomil

1.21 (0.48-3.04)

0

5

46,126

Amlodipine Besylate/Hydrochlorothiazide/Valsartan

1.09 (0.44-2.69)

2

4

45,227

Amlodipine Besylate/Olmesartan Medoxomil

1.14 (0.48-2.73)

4

6

109,162

Amlodipine Besylate/Valsartan

1.11 (0.47-2.66)

5

4

131,602

Ammonium Lactate

1.00 (0.45-2.20)

14

10

253,975

Amoxicillin

1.15 (0.98-1.34)

1,135

1,331

23,823,352

Amoxicillin/Clavulanate Potassium

0.94 (0.79-1.12)

1,018

973

14,424,100

Amoxicillin;Clarithromycin;Lansoprazole

1.14 (0.51-2.53)

11

13

292,731

Amphetamine Salt Combination

0.92 (0.72-1.19)

497

475

1,747,187

Ampicillin

1.06 (0.53-2.14)

25

29

342,457

Amylase/Lipase/Protease

1.08 (0.48-2.43)

8

15

89,745

Anagrelide Hydrochloride

1.01 (0.36-2.85)

0

1

4,771

Anastrozole

1.15 (0.49-2.65)

6

9

147,765

Antipyrine/Benzocaine

1.14 (0.65-2.00)

59

69

1,514,010

Apixaban

0.99 (0.38-2.55)

1

2

13,096

Aprepitant

1.07 (0.45-2.56)

5

5

97,226

Aripiprazole

0.43 (0.37-0.49)

2,613

1,143

545,749

Armodafinil

0.74 (0.37-1.48)

33

22

91,863

Asenapine

0.45 (0.27-0.76)

128

58

16,620

Aspirin

0.92 (0.41-2.03)

13

11

99,251

Aspirin/Butalbital/Caffeine

1.08 (0.55-2.13)

27

38

198,745

Aspirin/Butalbital/Caffeine/Codeine Phosphate

1.10 (0.51-2.37)

11

22

85,576

Aspirin/Dipyridamole

1.11 (0.43-2.88)

2

0

42,714

Atazanavir Sulfate

0.79 (0.33-1.88)

7

3

22,109

Atenolol

0.80 (0.53-1.21)

174

135

1,798,267

Atenolol/Chlorthalidone

1.33 (0.54-3.27)

2

4

180,006

Atomoxetine Hydrochloride

0.75 (0.52-1.09)

226

174

448,962

Atorvastatin Calcium

0.93 (0.63-1.37)

181

163

4,311,703

Atovaquone

0.98 (0.38-2.49)

1

3

13,661

Atovaquone/Proguanil Hydrochloride

1.12 (0.50-2.53)

11

8

409,726

Atropine Sulf/Hyoscyamine Sulf/Phenobarb/Scop Hydr

1.06 (0.54-2.09)

28

35

274,476

Atropine Sulfate

0.98 (0.42-2.24)

8

8

79,577

Atropine Sulfate/Diphenoxylate Hydrochloride

1.24 (0.75-2.04)

77

108

930,175

Azathioprine

1.15 (0.49-2.69)

5

8

127,616

Azelaic Acid

1.03 (0.49-2.15)

21

19

426,914

Azelaic Acid/Cu/Folic Acid/Niacinamide/Vit B6/Zinc

1.00 (0.35-2.84)

0

1

4,467

Azelastine Hydrochloride

1.28 (0.72-2.30)

47

67

1,435,228

Azelastine Hydrochloride/Fluticasone Propionate

1.08 (0.44-2.67)

4

1

86,856

Azilsartan Medoxomil/Chlorthalidone

1.07 (0.38-2.96)

0

1

8,826

Azithromycin

1.23 (1.07-1.43)

1,373

1,739

25,675,736

Bacitracin

0.79 (0.37-1.69)

21

9

149,321

Bacitracin Zinc/Polymyxin B Sulfate

0.94 (0.41-2.17)

9

5

96,943

Baclofen

0.85 (0.56-1.28)

163

144

473,369

Balsalazide Disodium

1.14 (0.44-2.92)

1

2

38,091

Barrier Skin Protectant

0.91 (0.36-2.32)

2

2

12,241

Beclomethasone Dipropionate

1.13 (0.61-2.08)

42

53

609,212

Benazepril Hydrochloride

1.04 (0.50-2.17)

21

20

418,437

Benazepril Hydrochloride/Hydrochlorothiazide

1.12 (0.47-2.71)

5

3

147,570

Benzonatate

1.03 (0.77-1.38)

338

357

4,166,447

Benzoyl Peroxide

1.02 (0.51-2.03)

29

28

495,547

Benzoyl Peroxide/Clindamycin Phosphate

1.14 (0.73-1.78)

112

137

1,289,925

Benzoyl Peroxide/Erythromycin

1.04 (0.56-1.95)

39

48

262,588

Benztropine Mesylate

0.50 (0.37-0.68)

462

238

88,723

Bepotastine Besilate

1.07 (0.44-2.64)

3

3

58,484

Besifloxacin Hydrochloride

0.96 (0.42-2.20)

9

6

103,045

Betamethasone Dipropionate

1.04 (0.52-2.10)

26

26

471,489

Betamethasone Dipropionate, Augmented

0.99 (0.47-2.08)

22

16

530,246

Betamethasone Dipropionate/Calcipotriene

1.11 (0.48-2.58)

6

9

121,623

Betamethasone Dipropionate/Clotrimazole

1.29 (0.83-2.02)

105

148

2,068,538

Betamethasone Valerate

1.15 (0.51-2.57)

11

10

408,729

Bethanechol Chloride

0.81 (0.35-1.88)

9

5

35,261

Bi Subcitrate K/Metronidazole/Tetracycline HCl

1.14 (0.44-2.97)

1

1

33,495

Bifidobacterium breve/Bifidobacterium infantis/Bif

0.97 (0.36-2.63)

0

2

5,713

Bimatoprost

1.35 (0.56-3.28)

1

8

138,105

Biotin/Blueberry/Ca/Cholecalciferol/Docosahexaenoi

0.97 (0.37-2.55)

2

0

15,524

Biotin/Ca Ascorbate/Ca Carbonate/Calcium Malate/Ca

1.05 (0.39-2.86)

1

0

13,420

Biotin/Ca Pantothenate/Cu/Docosahexaenoic Acid/Eic

1.05 (0.41-2.67)

2

1

30,412

Biotin/Ca Pantothenate/Fe Polysaccharide/Ferrous F

0.88 (0.34-2.27)

3

0

13,280

Biotin/Ca Pantothenate/Folic Acid/Niacinamide/Vit

1.08 (0.39-2.99)

0

1

10,021

Biotin/Ca/Cholecalciferol/Cu/Fe/Folic Acid/Iodine/

0.93 (0.39-2.26)

6

1

59,006

Biotin/Ca/Cholecalciferol/Docosahexaenoic Acid/Eic

1.04 (0.41-2.60)

3

1

44,824

Biotin/Cholecalciferol/Cu/Fe Polysaccharide/Folic

1.08 (0.40-2.93)

1

0

17,773

Biotin/Cholecalciferol/Docosahexaenoic Acid/Fe/Fol

1.00 (0.35-2.83)

0

1

4,318

Biotin/Folic Acid/Pyridoxine HCl/Vit B1/Vit B12/Vi

0.88 (0.31-2.54)

1

0

2,287

Bisacodyl

1.07 (0.41-2.75)

1

2

23,904

Bisoprolol Fumarate

1.01 (0.42-2.44)

5

3

72,511

Bisoprolol Fumarate/Hydrochlorothiazide

1.15 (0.50-2.63)

8

8

252,794

Bosentan

0.92 (0.32-2.60)

1

0

3,610

Brimonidine Tartrate

1.02 (0.44-2.34)

9

6

157,783

Brimonidine Tartrate/Brinzolamide

0.99 (0.35-2.82)

0

1

4,005

Brimonidine Tartrate/Timolol Maleate

1.20 (0.47-3.07)

1

2

56,680

Brinzolamide

1.08 (0.42-2.81)

2

0

35,463

Bromfenac

1.06 (0.45-2.47)

7

6

133,944

Bromocriptine Mesylate

0.87 (0.38-1.98)

9

9

38,654

Brompheniramine Mal/DM Hydrobrom/PSE HCl

1.30 (0.67-2.52)

29

43

1,098,811

Budesonide

1.19 (0.64-2.20)

42

50

1,659,061

Budesonide/Formoterol Fumarate

1.14 (0.65-1.99)

56

73

543,412

Bumetanide

1.06 (0.45-2.46)

6

8

91,197

Bupivacaine Hydrochloride

0.89 (0.33-2.42)

1

1

4,751

Buprenorphine

0.59 (0.33-1.06)

76

42

71,642

Buprenorphine/Naloxone

0.58 (0.39-0.86)

228

131

173,183

Bupropion Hydrochloride

0.55 (0.49-0.63)

2,593

1,463

3,328,953

Bupropion hydrobromide

0.77 (0.33-1.78)

6

9

8,749

Buspirone Hydrochloride

0.49 (0.40-0.60)

1,133

563

756,392

Butoconazole Nitrate

1.12 (0.48-2.61)

7

7

188,433

Butorphanol Tartrate

0.98 (0.43-2.23)

6

14

31,585

Ca Ascorbate/Calcium Threonate/Fe/Fe Polysaccharid

0.91 (0.35-2.34)

2

1

10,483

Ca Ascorbate/Calcium Threonate/Fe/Ferrous Fum/Foli

1.05 (0.40-2.76)

1

1

17,540

Ca Ascorbate/Calcium Threonate/Fe/Folic Acid/Succi

1.02 (0.38-2.69)

1

1

13,658

Ca Ascorbate/Calcium Threonate/Fe/Stomach, Desicca

1.04 (0.41-2.60)

1

4

22,043

Ca/Ca Pantothenate/DSS/Fe/Folic Acid/Niacinamide/V

0.90 (0.35-2.31)

3

0

15,235

Ca/Cholecalciferol/Choline/Fe/Folic Acid/Iodine/Vi

0.97 (0.35-2.70)

1

0

6,679

Ca/Cholecalciferol/Cu/DSS/Fe/Folic Acid/Iodine/Nia

1.05 (0.43-2.55)

5

2

96,953

Ca/Cholecalciferol/Cu/Fe/Folic Acid/Niacinamide/Py

0.74 (0.33-1.66)

15

5

58,408

Ca/Cholecalciferol/DSS/Docosahexaenoic Acid/Fe/Fol

1.17 (0.46-2.97)

2

1

67,647

Ca/Cholecalciferol/Docosahexaenoic Acid/Fe/Folic A

1.02 (0.43-2.43)

6

4

94,805

Ca/Cholecalciferol/Fe/Folic Acid/Iodine/Niacinamid

0.82 (0.33-2.02)

4

2

12,439

Ca/Cu/Fe/Folic Acid/Mg/Niacinamide/Vit A/Vit B1/Vi

1.41 (0.53-3.73)

0

1

94,727

Ca/Cu/Fe/Folic Acid/Mg/Vit A/Vit B1/Vit B12/Vit B2

0.96 (0.38-2.38)

3

2

25,870

Ca/Cu/Fe/Folic Acid/Niacinamide/Vit A/Vit B1/Vit B

0.82 (0.42-1.59)

40

27

333,864

Cabergoline

1.20 (0.47-3.06)

1

2

55,561

Calcipotriene

1.12 (0.48-2.64)

6

6

161,817

Calcitonin (Salmon)

0.93 (0.40-2.20)

7

4

63,845

Calcitriol

1.12 (0.49-2.55)

7

12

122,514

Calcium Acetate

0.81 (0.34-1.93)

8

1

38,753

Canagliflozin

1.12 (0.47-2.68)

3

7

68,293

Candesartan Cilexetil

1.22 (0.49-3.07)

2

2

98,895

Candesartan Cilexetil/Hydrochlorothiazide

1.30 (0.49-3.48)

0

1

50,418

Capecitabine

1.17 (0.45-3.04)

1

1

40,896

Captopril

1.03 (0.42-2.48)

4

4

56,093

Carbamazepine

0.47 (0.33-0.67)

358

164

228,283

Carbidopa/Levodopa

0.88 (0.41-1.91)

16

14

90,134

Carbinoxamine Maleate

1.19 (0.47-3.02)

2

1

76,991

Carisoprodol

1.63 (1.12-2.36)

147

276

1,274,536

Carvedilol

0.94 (0.54-1.65)

65

60

728,730

Cefaclor

1.21 (0.55-2.69)

10

15

317,693

Cefadroxil

0.87 (0.49-1.55)

64

50

852,606

Cefdinir

1.33 (0.96-1.85)

224

312

6,079,657

Cefixime

1.03 (0.50-2.12)

22

22

350,344

Cefpodoxime Proxetil

0.81 (0.38-1.75)

20

10

146,455

Cefprozil

1.06 (0.58-1.94)

48

48

1,340,154

Ceftibuten

1.15 (0.44-2.97)

2

0

54,289

Ceftriaxone Sodium

0.81 (0.34-1.95)

7

1

29,937

Cefuroxime Axetil

0.94 (0.64-1.39)

178

168

2,339,523

Celecoxib

1.19 (0.73-1.95)

84

107

1,613,880

Cephalexin

0.86 (0.73-1.01)

1,272

1,115

11,433,646

Certolizumab Pegol

0.90 (0.36-2.27)

2

3

12,201

Cetirizine HCl/PSE HCl

1.38 (0.63-3.03)

9

20

447,140

Cetirizine Hydrochloride

1.11 (0.61-2.05)

47

48

2,150,712

Cevimeline Hydrochloride

1.12 (0.45-2.75)

0

7

26,743

Chlordiazepoxide Hydrochloride

0.66 (0.44-1.01)

179

126

82,166

Chlordiazepoxide Hydrochloride/Clidinium Bromide

1.02 (0.49-2.13)

20

23

213,352

Chlorhexidine Gluconate

1.00 (0.68-1.47)

180

183

2,457,542

Chloroquine Phosphate

1.18 (0.49-2.86)

3

5

108,563

Chlorothiazide

1.06 (0.38-2.94)

0

1

7,830

Chlorpheniramine Mal/Hydrocod Bit/PSE HCl

1.16 (0.52-2.58)

10

14

245,607

Chlorpheniramine Polistirex/Hydrocodone Polistirex

1.42 (0.92-2.19)

109

173

2,192,637

Chlorpromazine Hydrochloride

0.65 (0.41-1.04)

130

93

38,896

Chlorthalidone

1.25 (0.54-2.93)

4

10

160,914

Chlorzoxazone

1.01 (0.50-2.03)

25

31

166,331

Cholecalciferol

0.83 (0.32-2.11)

2

2

5,900

Cholecalciferol/Cu/Docosahexaenoic Acid/Fe Polysac

0.99 (0.39-2.49)

3

1

32,623

Cholecalciferol/Cu/Fe/Ferrous Asparto Glycinate/Fo

0.98 (0.34-2.80)

0

1

3,485

Cholecalciferol/Fe/Folic Acid/Mg/Vit A/Vit B1/Vit

1.11 (0.41-3.00)

1

0

22,433

Cholestyramine

1.20 (0.60-2.42)

20

35

232,587

Chorionic Gonadotropin

1.29 (0.51-3.29)

1

2

95,467

Chorionic Gonadotropin Alfa, Recombinant

1.22 (0.49-3.09)

1

3

69,158

Ciclesonide

1.11 (0.52-2.38)

14

19

223,539

Ciclopirox

1.38 (0.67-2.87)

16

30

715,075

Ciclopirox Olamine

1.17 (0.49-2.79)

3

8

89,414

Cilostazol

1.21 (0.47-3.15)

1

1

54,322

Cimetidine

1.25 (0.56-2.77)

8

17

213,761

Ciprofloxacin

0.95 (0.80-1.14)

988

960

9,953,339

Ciprofloxacin Hydrochloride/Dexamethasone

1.23 (0.72-2.12)

62

82

1,646,992

Ciprofloxacin Hydrochloride/Hydrocortisone

1.27 (0.60-2.71)

13

23

384,311

Citalopram Hydrobromide

0.54 (0.47-0.61)

2,740

1,502

2,765,622

Citric Acid/Magnesium Oxide/Sodium Picosulfate

1.18 (0.48-2.91)

2

4

79,966

Clarithromycin

1.49 (0.98-2.26)

119

195

3,609,713

Clemastine Fumarate

1.15 (0.42-3.14)

0

1

17,686

Clindamycin Hydrochloride

1.01 (0.79-1.29)

485

501

4,303,696

Clindamycin Palmitate Hydrochloride

0.88 (0.39-2.00)

14

3

217,105

Clindamycin Phosphate

0.98 (0.69-1.40)

225

227

2,275,920

Clindamycin Phosphate/Tretinoin

1.04 (0.51-2.13)

22

25

274,368

Clobazam

0.85 (0.33-2.19)

1

3

4,954

Clobetasol Propionate

1.03 (0.63-1.69)

92

93

2,127,030

Clocortolone Pivalate

0.99 (0.43-2.32)

7

6

86,067

Clomiphene Citrate

1.34 (0.57-3.17)

3

9

212,806

Clomipramine Hydrochloride

0.84 (0.43-1.66)

29

34

33,856

Clonazepam

1.09 (0.96-1.23)

1,992

2,239

2,067,022

Clonidine

0.78 (0.40-1.52)

36

28

97,277

Clonidine Hydrochloride

0.70 (0.54-0.91)

513

366

741,447

Clopidogrel Hydrogen Sulfate

1.30 (0.71-2.39)

40

62

918,763

Clorazepate Dipotassium

0.89 (0.48-1.65)

44

46

104,975

Clotrimazole

0.82 (0.45-1.50)

56

41

460,076

Clozapine

0.44 (0.22-0.89)

43

15

7,603

Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Di

0.92 (0.35-2.39)

1

2

7,571

Codeine Phos/GG/PSE HCl

1.27 (0.56-2.88)

6

14

205,877

Codeine Phos/Phenyleph HCl/Promethazine HCl

1.21 (0.58-2.50)

18

27

416,985

Codeine Phosphate/Guaifenesin

1.26 (0.91-1.77)

221

294

4,032,412

Codeine Phosphate/Promethazine Hydrochloride

1.49 (1.00-2.20)

137

225

2,839,013

Codeine Sulfate

0.82 (0.34-1.99)

5

3

17,337

Colchicine

0.97 (0.47-1.99)

25

19

471,737

Colchicine/Probenecid

1.04 (0.39-2.74)

1

1

16,166

Colesevelam Hydrochloride

1.19 (0.52-2.73)

7

10

227,828

Colestipol Hydrochloride

1.04 (0.43-2.53)

4

3

64,642

Colistin Sulf/HC Ace/Neomycin Sulf/Thonzonium Brom

1.18 (0.46-3.01)

1

2

48,475

Collagenase

0.69 (0.32-1.52)

18

8

40,014

Conjugated Estrogens

1.32 (0.78-2.23)

64

95

1,461,340

Conjugated Estrogens Synthetic A

1.20 (0.47-3.05)

2

1

82,958

Conjugated Estrogens Synthetic B

1.19 (0.48-2.95)

0

6

41,111

Conjugated Estrogens/Medroxyprogesterone Acetate

1.22 (0.58-2.55)

16

25

379,250

Conjugated Estrogens;Conjugated Estrogens/Medroxyp

1.21 (0.45-3.27)

0

1

27,569

Copper/Folic Acid/Niacin/Zinc

0.74 (0.28-1.94)

3

0

3,467

Cream Base

1.05 (0.42-2.66)

0

5

17,113

Cream, Multi Ingredient

0.93 (0.44-1.98)

20

13

299,409

Cromolyn Sodium

0.97 (0.42-2.25)

8

6

92,829

Cu/Fe Polysaccharide/Ferrous Fum/Folic Acid/Mn/Na

1.03 (0.39-2.77)

0

2

9,741

Cyanocobalamin

0.98 (0.53-1.81)

44

47

301,188

Cyanocobalamin/Folic Acid/Iron Polysaccharide

0.95 (0.38-2.40)

3

1

24,487

Cyanocobalamin/Folic Acid/Pyridoxine

1.09 (0.47-2.50)

7

9

126,492

Cyclobenzaprine Hydrochloride

1.30 (1.08-1.57)

785

1,058

7,487,505

Cyclopentolate Hydrochloride

1.09 (0.44-2.67)

3

3

63,095

Cyclophosphamide

1.03 (0.38-2.82)

1

0

11,516

Cyclosporine

1.08 (0.54-2.15)

27

29

539,824

Cyclosporine, Modified

1.25 (0.47-3.36)

0

1

35,631

Cyproheptadine Hydrochloride

0.97 (0.53-1.78)

48

53

238,208

DM Hydrobrom/Promethazine HCl

1.09 (0.63-1.88)

66

75

1,133,028

DSS/Fe/Folic Acid/Vit B12/Vit C

1.09 (0.43-2.78)

2

1

41,059

Dabigatran Etexilate Mesylate

1.00 (0.41-2.42)

4

3

47,395

Dalfampridine

0.90 (0.35-2.34)

2

1

10,274

Dantrolene Sodium

0.81 (0.31-2.06)

2

2

4,947

Dapagliflozin Propanediol

1.12 (0.42-3.01)

1

0

23,485

Dapsone

0.99 (0.50-1.94)

31

32

308,935

Darifenacin Hydrobromide

1.20 (0.50-2.86)

2

9

76,003

Darunavir Ethanolate

0.93 (0.37-2.30)

2

4

14,695

Dasatinib

0.96 (0.33-2.77)

0

1

2,808

Desipramine Hydrochloride

0.79 (0.36-1.69)

17

14

42,192

Desloratadine

1.30 (0.63-2.72)

17

26

762,354

Desloratadine/Pseudoephedrine Sulfate

1.17 (0.48-2.81)

3

6

94,512

Desmopressin Acetate

0.95 (0.43-2.12)

13

9

163,671

Desogestrel/Ethinyl Estradiol;Desogestrel/Ethinyl

0.99 (0.42-2.35)

5

6

53,135

Desogestrel/Ethinyl Estradiol;Ethinyl Estradiol;Pl

1.05 (0.54-2.04)

31

35

386,512

Desogestrel/Ethinyl Estradiol;Placebo

1.01 (0.57-1.78)

59

64

505,639

Desonide

0.92 (0.49-1.73)

47

35

1,136,130

Desoximetasone

1.06 (0.51-2.18)

23

21

602,912

Desvenlafaxine

0.70 (0.51-0.97)

334

242

337,896

Dexamethasone

1.26 (0.76-2.10)

73

103

1,279,987

Dexamethasone/Neomycin Sulfate/Polymyxin B Sulfate

1.03 (0.53-2.01)

33

33

594,196

Dexamethasone/Tobramycin

1.20 (0.72-2.02)

72

92

1,724,610

Dexlansoprazole

1.04 (0.53-2.03)

30

34

332,620

Dexmethylphenidate Hydrochloride

0.92 (0.52-1.61)

63

61

331,037

Dextroamphetamine Sulfate

0.82 (0.40-1.69)

25

20

97,613

Dextromethorphan Hydrobromide/Quinidine Sulfate

0.62 (0.25-1.56)

5

0

2,539

Diazepam

1.28 (1.03-1.60)

547

736

3,074,559

Diclofenac

0.88 (0.35-2.18)

2

4

10,101

Diclofenac Epolamine

1.03 (0.51-2.09)

23

30

164,974

Diclofenac Potassium

1.30 (0.69-2.45)

31

56

351,891

Diclofenac Sodium

1.19 (0.86-1.64)

242

302

2,717,783

Diclofenac Sodium/Misoprostol

1.11 (0.49-2.50)

9

12

177,862

Dicloxacillin Sodium

0.96 (0.45-2.05)

19

14

306,814

Dicyclomine Hydrochloride

1.04 (0.72-1.51)

192

211

1,237,571

Dienogest/Estradiol Valerate;Dienogest/Estradiol V

0.93 (0.38-2.25)

3

5

20,231

Diethylpropion Hydrochloride

1.04 (0.41-2.64)

1

3

21,739

Diflorasone Diacetate

1.31 (0.51-3.33)

1

2

104,065

Diflunisal

1.10 (0.50-2.45)

9

16

112,703

Difluprednate

1.30 (0.55-3.07)

2

10

122,503

Digoxin

1.06 (0.49-2.29)

14

15

232,172

Dihydroergotamine Mesylate

0.95 (0.42-2.14)

7

14

30,108

Diltiazem Hydrochloride

0.86 (0.47-1.57)

56

42

690,087

Dimethyl Fumarate

1.04 (0.38-2.84)

1

0

12,286

Diphenhydramine Hydrochloride

0.62 (0.31-1.24)

40

18

79,127

Dipyridamole

1.04 (0.39-2.79)

0

2

10,686

Disinfectant Prep Pad

1.09 (0.42-2.82)

2

0

36,356

Disopyramide Phosphate

0.94 (0.34-2.64)

1

0

4,796

Disulfiram

0.40 (0.25-0.64)

189

69

42,805

Divalproex Sodium

0.45 (0.37-0.54)

1,395

629

487,123

Docosahexaenoic Acid/Eicosapentaenoic Acid/Phospha

0.77 (0.30-1.96)

3

1

5,200

Docosahexaenoic Acid/Eicosapentaenoic Acid;Prenata

1.06 (0.42-2.65)

3

1

51,200

Docosahexaenoic Acid;Prenatal Vitamins

0.93 (0.38-2.30)

5

0

44,541

Docusate Sodium

0.85 (0.37-1.95)

9

6

43,304

Dolutegravir Sodium

0.81 (0.31-2.15)

1

2

2,814

Donepezil Hydrochloride

0.68 (0.33-1.42)

27

16

45,894

Dornase Alfa

1.08 (0.39-2.98)

0

1

9,663

Dorzolamide Hydrochloride

1.13 (0.42-3.04)

1

0

25,605

Dorzolamide Hydrochloride/Timolol Maleate

1.06 (0.44-2.55)

5

3

98,457

Doxazosin Mesylate

0.94 (0.42-2.10)

14

7

229,267

Doxepin Hydrochloride

0.68 (0.48-0.97)

266

185

274,789

Doxycycline

1.02 (0.82-1.26)

656

685

7,051,539

Doxylamine Succinate/Pyridoxine Hydrochloride

0.98 (0.37-2.57)

2

0

16,422

Dronabinol

0.85 (0.39-1.84)

14

15

40,634

Drospirenone/Estradiol

0.94 (0.36-2.42)

2

1

13,645

Drospirenone/Ethinyl Estradiol/Levomefolate Ca;Lev

1.04 (0.48-2.27)

12

17

117,789

Drospirenone/Ethinyl Estradiol;Placebo

1.14 (0.77-1.71)

149

181

1,702,277

Duloxetine Hydrochloride

0.64 (0.54-0.75)

1,382

898

1,435,267

Dutasteride

1.07 (0.45-2.57)

6

2

144,036

Dutasteride/Tamsulosin Hydrochloride

1.18 (0.43-3.19)

0

1

21,358

Econazole Nitrate

1.12 (0.55-2.31)

22

24

617,920

Efavirenz

1.12 (0.42-2.96)

0

2

18,422

Efavirenz/Emtricitabine/Tenofovir Disoproxil Fum

1.12 (0.47-2.67)

2

9

46,844

Eletriptan Hydrobromide

1.13 (0.59-2.17)

31

45

267,082

Emtricitabine/Rilpivirine Hydrochloride/Tenofovir

0.91 (0.35-2.38)

1

2

7,080

Emtricitabine/Tenofovir Disoproxil Fumarate

0.96 (0.44-2.10)

11

16

55,114

Enalapril Maleate

0.89 (0.45-1.76)

34

24

481,400

Enalapril Maleate/Hydrochlorothiazide

1.04 (0.43-2.52)

4

3

62,695

Enoxaparin Sodium

0.79 (0.50-1.26)

124

97

552,475

Entacapone

0.94 (0.34-2.64)

1

0

4,873

Entecavir

1.08 (0.39-2.99)

0

1

10,057

Epinastine Hydrochloride

1.07 (0.44-2.62)

5

1

115,357

Epinephrine

0.95 (0.57-1.56)

93

85

1,513,449

Epoetin Alfa

1.09 (0.43-2.72)

1

4

31,187

Ergocalciferol

0.95 (0.68-1.31)

267

258

2,297,264

Erythromycin

1.11 (0.70-1.76)

106

122

2,030,064

Erythromycin Ethylsuccinate

0.94 (0.42-2.13)

13

5

234,844

Erythromycin Stearate

0.97 (0.43-2.20)

11

7

156,375

Escitalopram Oxalate

0.61 (0.54-0.69)

2,654

1,657

3,124,443

Esomeprazole Magnesium

0.94 (0.65-1.38)

195

185

2,555,630

Esomeprazole Magnesium/Naproxen

1.01 (0.42-2.45)

5

2

74,216

Estazolam

0.62 (0.29-1.34)

21

12

16,357

Esterified Estrogens

0.98 (0.39-2.47)

3

1

30,637

Esterified Estrogens/Methyltestosterone

1.18 (0.56-2.49)

15

25

242,421

Estradiol

1.25 (0.82-1.89)

129

172

2,274,253

Estradiol Acetate

1.06 (0.41-2.70)

2

1

32,983

Estradiol Cypionate

0.89 (0.34-2.30)

2

1

9,051

Estradiol Valerate

1.05 (0.41-2.69)

0

4

15,738

Estradiol, Micronized

1.23 (0.46-3.31)

0

1

31,240

Estradiol/Levonorgestrel

1.10 (0.44-2.75)

1

4

33,521

Estradiol/Norethindrone Acetate

1.14 (0.51-2.54)

10

14

219,814

Estriol

1.08 (0.44-2.66)

3

3

61,085

Estropipate

1.20 (0.47-3.07)

1

2

56,197

Eszopiclone

0.87 (0.65-1.17)

346

315

713,929

Etanercept

1.10 (0.49-2.46)

9

13

147,426

Ethinyl Estradiol/Ethynodiol Diacetate;Placebo

1.10 (0.50-2.40)

11

17

145,546

Ethinyl Estradiol/Etonogestrel

1.29 (0.78-2.12)

75

113

784,211

Ethinyl Estradiol/Levonorgestrel

1.07 (0.63-1.84)

67

80

523,490

Ethinyl Estradiol/Levonorgestrel;Ethinyl Estradiol

1.31 (0.57-3.01)

5

12

239,566

Ethinyl Estradiol/Levonorgestrel;Placebo

1.02 (0.65-1.61)

112

120

1,002,907

Ethinyl Estradiol/Norelgestromin

1.13 (0.62-2.05)

45

60

417,554

Ethinyl Estradiol/Norethindrone

1.11 (0.52-2.37)

14

22

167,501

Ethinyl Estradiol/Norethindrone Ace;Ethinyl Estrad

0.97 (0.43-2.18)

11

9

129,526

Ethinyl Estradiol/Norethindrone Ace;Ferrous Fum

1.29 (0.86-1.93)

137

194

1,584,975

Ethinyl Estradiol/Norethindrone Acetate

1.07 (0.59-1.92)

49

58

471,553

Ethinyl Estradiol/Norethindrone;Ethinyl Estradiol/

1.06 (0.48-2.34)

12

13

201,213

Ethinyl Estradiol/Norethindrone;Ferrous Fumarate

1.19 (0.56-2.54)

12

25

150,178

Ethinyl Estradiol/Norethindrone;Placebo

1.38 (0.75-2.54)

35

65

556,993

Ethinyl Estradiol/Norgestimate

1.02 (0.48-2.15)

15

22

93,516

Ethinyl Estradiol/Norgestimate;Ethinyl Estradiol/N

1.21 (0.86-1.70)

212

273

2,235,851

Ethinyl Estradiol/Norgestimate;Placebo

1.05 (0.68-1.62)

126

143

785,663

Ethinyl Estradiol/Norgestrel;Placebo

1.40 (0.75-2.64)

30

60

477,236

Ethinyl Estradiol;Ethinyl Estradiol/Levonorgestrel

1.01 (0.53-1.89)

39

45

251,121

Ethinyl Estradiol;Ethinyl Estradiol/Norethindrone

1.05 (0.55-2.01)

34

43

250,951

Ethosuximide

1.09 (0.40-3.01)

0

1

10,886

Etodolac

1.08 (0.64-1.83)

73

83

1,069,182

Etonogestrel

0.80 (0.32-2.01)

3

2

7,534

Etravirine

0.92 (0.35-2.44)

0

3

5,115

Everolimus

0.84 (0.31-2.26)

2

0

4,719

Exenatide

1.12 (0.47-2.66)

7

3

249,008

Ezetimibe

1.22 (0.57-2.59)

16

19

719,714

Ezetimibe/Simvastatin

1.36 (0.60-3.10)

8

10

752,804

Famciclovir

1.07 (0.52-2.19)

22

24

386,399

Famotidine

0.67 (0.44-1.01)

185

117

729,987

Famotidine/Ibuprofen

1.09 (0.44-2.73)

1

4

31,895

Felbamate

0.80 (0.29-2.17)

2

0

3,006

Felodipine

1.05 (0.44-2.49)

6

4

111,944

Fenofibrate

1.16 (0.64-2.09)

49

60

1,168,327

Fenofibric Acid

1.31 (0.59-2.93)

7

18

238,279

Fentanyl

0.78 (0.50-1.24)

128

103

313,162

Fentanyl Citrate

0.91 (0.36-2.31)

3

1

18,206

Ferrous Sulfate

0.86 (0.36-2.07)

5

3

23,117

Fesoterodine Fumarate

0.97 (0.40-2.37)

4

3

40,220

Fexofenadine HCl/PSE HCl

1.23 (0.64-2.39)

31

39

1,362,877

Fexofenadine Hydrochloride

1.18 (0.74-1.88)

99

120

2,972,286

Finasteride

1.33 (0.59-3.01)

6

16

255,868

Fingolimod Hydrochloride

0.87 (0.34-2.21)

2

2

8,407

Flecainide Acetate

1.17 (0.47-2.88)

2

4

73,186

Fluconazole

1.15 (0.93-1.44)

583

695

6,112,389

Fludrocortisone Acetate

0.90 (0.43-1.90)

18

21

64,962

Flunisolide

1.18 (0.52-2.69)

8

11

249,990

Fluocinolone Acetonide

1.55 (0.74-3.26)

11

33

550,385

Fluocinonide

1.02 (0.58-1.80)

61

59

1,415,681

Fluorometholone

1.03 (0.48-2.19)

17

16

285,966

Fluorouracil

1.24 (0.54-2.82)

8

10

377,408

Fluoxetine Hydrochloride

0.68 (0.60-0.76)

2,707

1,874

2,478,912

Fluoxetine Hydrochloride/Olanzapine

0.54 (0.28-1.04)

52

25

28,703

Fluphenazine Hydrochloride

0.62 (0.30-1.29)

23

20

6,610

Flurandrenolide

1.08 (0.45-2.58)

5

4

103,901

Flurazepam Hydrochloride

0.92 (0.47-1.80)

29

38

51,154

Flurbiprofen

1.09 (0.49-2.42)

9

15

109,952

Fluticasone Furoate

1.22 (0.57-2.62)

14

19

494,166

Fluticasone Propionate

1.15 (0.92-1.44)

569

673

10,491,110

Fluticasone Propionate, Micronized

0.80 (0.31-2.02)

3

1

6,744

Fluticasone Propionate/Salmeterol Xinafoate

1.01 (0.68-1.49)

168

172

2,250,358

Fluvoxamine Maleate

0.82 (0.51-1.32)

112

105

85,584

Foam, Multi Ingredient

1.09 (0.40-2.95)

1

0

18,668

Folic Acid

0.40 (0.28-0.59)

343

122

682,742

Folic Acid/Na Fluoride/Vit A/Vit B1/Vit B12/Vit B2

1.49 (0.59-3.73)

1

3

274,384

Follicle Stimulating Hormone/Luteinizing Hormone

1.35 (0.51-3.59)

0

1

67,061

Follitropin Alfa

1.24 (0.47-3.24)

0

2

41,274

Follitropin Beta

1.08 (0.43-2.70)

3

1

59,139

Fondaparinux Sodium

1.08 (0.43-2.69)

2

3

42,257

Formoterol Fumarate

1.14 (0.47-2.76)

2

7

59,431

Formoterol Fumarate/Mometasone Furoate

1.09 (0.50-2.40)

11

17

141,762

Fosamprenavir Calcium

0.91 (0.34-2.44)

1

1

5,322

Fosinopril Sodium

1.30 (0.51-3.31)

1

2

99,369

Frovatriptan Succinate

0.99 (0.46-2.17)

12

17

79,775

Furosemide

0.87 (0.59-1.28)

192

167

1,623,290

Gabapentin

0.64 (0.54-0.76)

1,440

937

2,511,056

Gabapentin Enacarbil

0.81 (0.32-2.07)

2

2

5,070

Ganciclovir

0.92 (0.37-2.27)

3

3

19,721

Ganirelix Acetate

1.20 (0.45-3.18)

1

0

39,927

Gatifloxacin

1.46 (0.70-3.02)

15

32

774,950

Gemfibrozil

1.20 (0.59-2.45)

20

29

442,893

Gentamicin Sulfate

1.14 (0.65-2.01)

56

67

1,215,886

Glatiramer Acetate

1.17 (0.48-2.84)

1

7

50,392

Glimepiride

1.14 (0.57-2.30)

24

29

579,523

Glipizide

1.22 (0.63-2.34)

31

43

738,154

Glipizide/Metformin Hydrochloride

1.17 (0.44-3.13)

1

0

34,539

Glucagon Hydrochloride

1.09 (0.52-2.28)

16

25

142,750

Glucose Meter

0.73 (0.38-1.41)

46

23

403,048

Glucose Meter Test Control

1.22 (0.49-3.02)

1

5

70,231

Glucose Meter Test Control Strips

1.04 (0.71-1.54)

167

178

2,561,638

Glucose, Blood Test

1.06 (0.53-2.11)

28

28

610,911

Glyburide

0.88 (0.42-1.83)

25

13

421,487

Glyburide/Metformin Hydrochloride

1.07 (0.46-2.48)

9

5

255,665

Glycopyrrolate

0.79 (0.36-1.72)

18

9

94,100

Golimumab

0.90 (0.35-2.28)

2

2

10,839

Gramicidin/Neomycin Sulfate/Polymyxin B Sulfate

0.90 (0.40-2.06)

11

6

102,997

Granisetron

0.98 (0.35-2.71)

1

0

6,885

Griseofulvin, Microcrystalline

1.44 (0.58-3.57)

1

4

217,416

Griseofulvin, Ultramicrocrystalline

1.07 (0.44-2.62)

4

2

78,841

Guaifenesin/Pseudoephedrine Hydrochloride

1.28 (0.66-2.47)

31

42

1,460,438

Guanfacine Hydrochloride

0.58 (0.38-0.90)

182

103

215,938

HC/Neomycin Sulf/Polymyxin B Sulf

0.99 (0.64-1.53)

134

133

2,129,522

HPV Vac Recomb Quadrivalent (Types 6, 11, 16, 18)

0.86 (0.35-2.12)

3

4

12,771

Halcinonide

1.03 (0.41-2.60)

2

2

29,361

Halobetasol Propionate

1.33 (0.55-3.25)

3

4

255,301

Haloperidol

0.59 (0.39-0.89)

195

123

40,263

Heparin Sodium

1.07 (0.43-2.63)

2

4

39,158

Hepatitis A Vaccine, Inactivated

1.06 (0.39-2.87)

1

0

14,041

Hepatitis B Vaccine Recombinant

1.03 (0.38-2.81)

1

0

11,196

Homatropine Methylbromide/Hydrocodone Bitartrate

1.30 (0.79-2.15)

76

111

1,505,803

Hyaluronate Sodium

1.25 (0.49-3.21)

0

3

50,824

Hyaluronic Acid

1.00 (0.39-2.59)

1

2

14,542

Hydralazine Hydrochloride

0.70 (0.34-1.44)

30

12

145,227

Hydralazine Hydrochloride/Isosorbide Dinitrate

1.02 (0.36-2.88)

0

1

5,659

Hydrochlorothiazide

0.80 (0.58-1.12)

281

222

3,366,115

Hydrochlorothiazide/Irbesartan

1.22 (0.50-3.01)

4

1

204,934

Hydrochlorothiazide/Lisinopril

1.24 (0.74-2.09)

71

95

1,795,157

Hydrochlorothiazide/Losartan Potassium

1.13 (0.57-2.26)

27

31

717,475

Hydrochlorothiazide/Metoprolol Tartrate

1.09 (0.41-2.85)

1

1

23,506

Hydrochlorothiazide/Moexipril Hydrochloride

1.17 (0.45-3.09)

0

2

27,417

Hydrochlorothiazide/Olmesartan Medoxomil

1.20 (0.55-2.62)

12

15

427,609

Hydrochlorothiazide/Quinapril Hydrochloride

1.06 (0.42-2.69)

3

0

49,762

Hydrochlorothiazide/Spironolactone

1.03 (0.42-2.48)

4

4

56,255

Hydrochlorothiazide/Telmisartan

1.20 (0.48-3.00)

3

1

126,681

Hydrochlorothiazide/Triamterene

1.03 (0.58-1.83)

58

57

1,381,911

Hydrochlorothiazide/Valsartan

1.26 (0.57-2.78)

12

13

782,356

Hydrocodone Bitartrate

1.01 (0.38-2.73)

0

2

8,351

Hydrocodone Bitartrate/Ibuprofen

1.16 (0.73-1.87)

94

121

885,930

Hydrocortisone

1.02 (0.65-1.59)

119

122

1,920,390

Hydrocortisone Acetate

1.11 (0.62-1.99)

52

60

1,011,406

Hydrocortisone Acetate/Lidocaine Hydrochloride

1.05 (0.43-2.58)

4

2

71,595

Hydrocortisone Acetate/Pramoxine Hydrochloride

0.98 (0.51-1.89)

36

33

546,467

Hydrocortisone Butyrate

1.11 (0.49-2.53)

10

8

322,732

Hydrocortisone Valerate

1.15 (0.56-2.39)

20

24

547,791

Hydrocortisone/Iodoquinol

1.29 (0.49-3.36)

0

2

55,907

Hydromorphone Hydrochloride

1.46 (0.94-2.28)

94

168

527,168

Hydroquinone

1.31 (0.50-3.44)

1

0

80,337

Hydroxychloroquine Sulfate

1.01 (0.50-2.01)

28

28

378,266

Hydroxyurea

1.04 (0.40-2.69)

1

2

19,818

Hydroxyzine Hydrochloride

0.53 (0.42-0.65)

953

501

2,044,541

Hydroxyzine Pamoate

0.39 (0.33-0.46)

1,886

738

744,133

Hyoscyamine Sulf/Methenamine/Methylene Blue/Na Pho

1.32 (0.59-2.95)

6

19

185,158

Hyoscyamine Sulfate

1.08 (0.69-1.69)

114

131

1,078,941

Hypromellose

1.00 (0.35-2.84)

0

1

4,646

Ibandronate Sodium

1.23 (0.54-2.80)

7

11

258,248

Ibuprofen

1.12 (0.94-1.33)

1,005

1,156

10,329,084

Iloperidone

0.53 (0.24-1.16)

17

10

3,449

Imipramine Hydrochloride

0.92 (0.47-1.79)

32

34

130,130

Imipramine Pamoate

0.71 (0.30-1.71)

6

3

8,621

Imiquimod

1.18 (0.60-2.35)

26

34

650,341

Immune Globulin

0.99 (0.35-2.82)

0

1

4,002

Indomethacin

1.16 (0.69-1.94)

74

93

1,093,097

Influenza Virus Vaccine

0.95 (0.63-1.45)

146

139

2,058,810

Ingenol Mebutate

1.14 (0.43-3.01)

0

2

21,685

Insulin Aspart, Recombinant

1.01 (0.55-1.84)

48

52

433,971

Insulin Aspart/Insulin Aspart Protamine

1.16 (0.48-2.79)

3

6

90,096

Insulin Detemir

0.95 (0.46-1.97)

22

20

221,432

Insulin Glargine, Recombinant

1.03 (0.62-1.72)

81

87

878,276

Insulin Glulisine

1.04 (0.42-2.58)

3

2

46,473

Insulin Human Isophane (NPH)

1.24 (0.53-2.88)

5

9

201,088

Insulin Human Isophane (NPH)/Insulin Human Regular

1.11 (0.48-2.56)

6

10

109,508

Insulin Human Regular

0.87 (0.41-1.86)

19

13

147,531

Insulin Lispro, Recombinant

1.03 (0.56-1.89)

45

50

428,572

Insulin Lispro/Insulin Lispro Protamine

1.07 (0.45-2.56)

4

6

68,843

Interferon Beta-1A

1.07 (0.43-2.65)

3

2

55,974

Ipratropium Bromide

1.06 (0.56-2.02)

36

40

537,007

Irbesartan

1.13 (0.50-2.55)

10

10

302,470

Isoniazid

0.89 (0.38-2.06)

9

5

67,521

Isopropyl Alcohol

1.07 (0.39-2.96)

0

1

8,830

Isosorbide Dinitrate

1.04 (0.41-2.62)

2

2

30,730

Isosorbide Mononitrate

1.28 (0.59-2.78)

10

22

252,305

Isotretinoin

1.43 (0.70-2.95)

14

36

359,517

Itraconazole

1.17 (0.48-2.85)

3

4

102,885

Ivermectin

1.14 (0.49-2.69)

3

10

65,784

K Cl/Na Bicarb/Na Cl/Na Sulf/PEG

1.20 (0.59-2.46)

20

29

469,609

K Cl/Na Bicarb/Na Cl/Na Sulf/Polyethylene Glycol 3

1.19 (0.63-2.23)

36

49

654,780

K Cl/Na Bicarb/Na Cl/Polyethylene Glycol 3350

1.18 (0.67-2.09)

54

67

1,381,308

K Cl/Na Cl/Na Sulf/Polyethylene Glycol 3350;Na Asc

1.20 (0.66-2.18)

46

61

1,007,790

K Phos/Na Phos, Dibasic/Na Phos, Monobasic

0.87 (0.35-2.15)

3

3

13,696

Ketamine Hydrochloride

0.95 (0.42-2.14)

9

11

60,351

Ketoconazole

1.16 (0.75-1.80)

117

142

2,134,446

Ketoprofen

0.96 (0.46-1.98)

22

22

188,358

Ketorolac Tromethamine

1.22 (0.84-1.77)

172

229

1,224,920

Kit, Blood Glucose Test

1.07 (0.44-2.59)

4

4

77,186

L-Methylfolate/Schizochytrium

0.74 (0.32-1.73)

6

9

7,039

Labetalol Hydrochloride

0.93 (0.45-1.92)

23

19

236,812

Lacosamide

0.70 (0.31-1.57)

13

7

20,516

Lactulose

0.91 (0.53-1.58)

68

66

313,053

Lamivudine

1.08 (0.41-2.80)

0

3

16,814

Lamivudine/Zidovudine

0.99 (0.39-2.55)

2

1

21,109

Lamotrigine

0.54 (0.46-0.63)

1,937

1,071

707,830

Lansoprazole

1.28 (0.83-1.97)

115

160

1,895,631

Lanthanum Carbonate

0.96 (0.36-2.56)

1

1

8,833

Latanoprost

1.12 (0.48-2.62)

8

5

280,748

Leflunomide

1.03 (0.42-2.51)

4

3

60,435

Letrozole

1.29 (0.51-3.22)

2

2

140,622

Leucovorin Calcium

1.01 (0.40-2.52)

2

3

26,233

Leuprolide Acetate

1.22 (0.52-2.84)

4

11

124,247

Levalbuterol Hydrochloride

1.34 (0.65-2.76)

17

30

641,867

Levalbuterol Tartrate

1.09 (0.58-2.03)

40

48

501,444

Levetiracetam

0.87 (0.55-1.37)

122

114

276,391

Levobunolol Hydrochloride

0.93 (0.35-2.45)

2

0

10,622

Levocarnitine

0.81 (0.33-1.95)

5

3

14,826

Levocetirizine Dihydrochloride

1.30 (0.65-2.58)

23

38

632,641

Levofloxacin

0.95 (0.75-1.21)

530

512

6,316,758

Levomefolate Ca/Methylcobalamin/Pyridoxal Phos

1.07 (0.43-2.63)

3

3

56,069

Levomefolate Calcium

0.57 (0.31-1.06)

60

34

28,462

Levomilnacipran Hydrochloride

0.63 (0.29-1.37)

17

12

9,772

Levonorgestrel

1.03 (0.51-2.07)

23

31

141,419

Levothyroxine Sodium

1.03 (0.79-1.34)

414

435

4,904,302

Lidocaine

0.89 (0.65-1.21)

319

289

1,924,284

Lidocaine/Prilocaine

1.14 (0.55-2.38)

18

24

346,411

Linaclotide

0.71 (0.33-1.52)

21

10

56,707

Linagliptin

1.07 (0.43-2.67)

2

3

40,225

Linezolid

0.77 (0.36-1.67)

18

11

61,695

Liothyronine Sodium

0.88 (0.49-1.55)

62

58

223,907

Liraglutide

0.93 (0.42-2.05)

15

10

184,560

Lisdexamfetamine Dimesylate

0.89 (0.64-1.22)

288

266

766,878

Lisinopril

0.70 (0.54-0.92)

499

345

4,858,476

Lithium Carbonate

0.43 (0.35-0.53)

1,229

542

241,196

Loperamide Hydrochloride

0.78 (0.37-1.64)

22

14

83,101

Lopinavir/Ritonavir

1.02 (0.40-2.60)

1

3

19,276

Loratadine

0.96 (0.45-2.08)

16

15

161,647

Loratadine/Pseudoephedrine Sulfate

1.09 (0.44-2.71)

2

3

44,619

Lorazepam

0.90 (0.79-1.03)

1,807

1,679

2,956,395

Lorcaserin Hydrochloride

1.02 (0.39-2.70)

1

1

14,452

Losartan Potassium

0.97 (0.58-1.62)

85

81

1,231,348

Loteprednol Etabonate

1.06 (0.53-2.14)

27

26

699,498

Loteprednol Etabonate/Tobramycin

1.14 (0.49-2.64)

7

7

207,793

Lovastatin

1.26 (0.61-2.60)

19

27

746,212

Lovastatin/Niacin

1.19 (0.46-3.06)

2

0

69,980

Loxapine Succinate

0.58 (0.27-1.24)

20

17

4,083

Lubiprostone

0.95 (0.47-1.90)

27

29

156,973

Lurasidone Hydrochloride

0.51 (0.34-0.76)

241

129

30,026

Magnesium Sulfate/Potassium Sulfate/Sodium Sulfate

1.02 (0.51-2.02)

30

27

650,720

Malathion

1.05 (0.44-2.48)

5

6

76,259

Maraviroc

0.93 (0.32-2.73)

0

1

1,855

Meclizine Hydrochloride

1.24 (0.74-2.06)

72

99

1,186,951

Medical Food

1.03 (0.42-2.54)

3

3

44,178

Medroxyprogesterone Acetate

1.02 (0.69-1.51)

169

181

1,308,599

Mefenamic Acid

1.07 (0.47-2.44)

6

12

69,459

Mefloquine Hydrochloride

1.23 (0.51-2.99)

4

3

206,182

Megestrol Acetate

0.99 (0.45-2.16)

13

15

114,654

Meloxicam

1.04 (0.78-1.38)

350

373

3,770,991

Memantine Hydrochloride

0.62 (0.29-1.34)

22

8

32,001

Meperidine Hydrochloride

1.29 (0.66-2.53)

23

44

291,422

Mercaptopurine

1.17 (0.47-2.90)

1

5

53,676

Mesalamine

1.01 (0.50-2.03)

27

27

372,629

Mestranol/Norethindrone;Placebo

0.87 (0.36-2.11)

5

2

25,574

Metaxalone

1.29 (0.86-1.94)

135

192

1,484,746

Metformin Hydrochloride

0.82 (0.58-1.15)

267

214

3,727,527

Metformin Hydrochloride/Pioglitazone Hydrochloride

1.20 (0.49-2.96)

3

3

128,564

Metformin Hydrochloride/Saxagliptin Hydrochloride

1.06 (0.44-2.58)

3

5

52,071

Metformin Hydrochloride/Sitagliptin Phosphate

1.18 (0.52-2.68)

8

11

246,453

Methadone Hydrochloride

0.99 (0.54-1.82)

44

55

130,415

Methenamine Hippurate

1.01 (0.38-2.73)

0

2

8,412

Methimazole

0.85 (0.39-1.88)

16

8

138,994

Methocarbamol

0.86 (0.63-1.17)

322

283

1,417,856

Methotrexate Sodium

1.22 (0.59-2.50)

19

30

388,381

Methscopolamine Bromide

1.11 (0.45-2.75)

1

5

36,294

Methylcobalamin

0.94 (0.38-2.38)

1

4

11,438

Methyldopa

1.36 (0.52-3.53)

0

2

83,493

Methylergonovine Maleate

1.05 (0.49-2.24)

15

20

157,705

Methylphenidate

0.85 (0.65-1.12)

418

367

1,431,289

Methylprednisolone

1.22 (0.97-1.54)

526

666

8,296,031

Metoclopramide Hydrochloride

1.11 (0.75-1.66)

154

183

1,307,081

Metolazone

1.01 (0.46-2.25)

10

14

88,257

Metoprolol

0.86 (0.65-1.14)

411

358

3,379,045

Metronidazole

1.10 (0.89-1.37)

619

703

5,717,087

Mexiletine Hydrochloride

0.90 (0.34-2.34)

1

2

6,287

Miconazole Nitrate/Petrolatum, White/Zinc Oxide

1.29 (0.48-3.45)

0

1

46,806

Midodrine Hydrochloride

0.86 (0.39-1.92)

11

13

35,724

Milnacipran Hydrochloride

0.71 (0.33-1.50)

23

11

67,691

Minocycline Hydrochloride

1.17 (0.79-1.73)

155

194

1,725,017

Minoxidil

0.95 (0.39-2.33)

4

2

35,143

Mirabegron

0.96 (0.38-2.43)

2

2

17,514

Mirtazapine

0.38 (0.32-0.45)

1,711

654

428,011

Misoprostol

1.01 (0.51-1.99)

29

31

301,807

Modafinil

0.81 (0.46-1.43)

69

57

235,665

Moexipril Hydrochloride

1.23 (0.46-3.30)

0

1

30,075

Mometasone Furoate

1.16 (0.79-1.69)

170

201

4,822,813

Montelukast Sodium

1.39 (0.94-2.07)

139

208

3,936,069

Morphine Sulfate

1.07 (0.68-1.68)

108

130

388,094

Moxifloxacin Hydrochloride

0.99 (0.68-1.45)

188

187

3,707,365

Multivitamin and Fluoride

1.21 (0.45-3.26)

0

1

26,168

Multivitamin, Minerals, and Nutriceuticals

1.03 (0.38-2.81)

1

0

10,972

Mupirocin

1.03 (0.77-1.37)

346

365

4,038,123

Mycophenolate Mofetil

0.98 (0.42-2.26)

8

6

95,146

Mycophenolate Sodium

1.01 (0.38-2.68)

1

1

13,517

Na Fluoride/Vit A/Vit B1/Vit B12/Vit B2/Vit B6/Vit

1.49 (0.57-3.92)

0

1

144,899

Na Phos, Dibasic/Na Phos, Monobasic

1.08 (0.49-2.37)

14

11

412,319

Nabumetone

1.26 (0.77-2.05)

81

114

1,172,327

Nadolol

1.11 (0.52-2.38)

13

23

126,397

Naftifine Hydrochloride

1.17 (0.50-2.75)

6

6

216,903

Naloxone Hydrochloride/Pentazocine Hydrochloride

0.97 (0.44-2.12)

11

16

59,205

Naltrexone

0.42 (0.30-0.58)

441

184

71,648

Naproxen

1.14 (0.92-1.40)

659

772

6,849,599

Naproxen Sodium/Sumatriptan Succinate

1.04 (0.49-2.23)

14

22

99,041

Naratriptan Hydrochloride

1.14 (0.50-2.59)

5

15

69,025

Nateglinide

1.05 (0.43-2.58)

3

3

49,280

Nebivolol Hydrochloride

1.13 (0.57-2.23)

26

35

349,953

Nefazodone Hydrochloride

0.79 (0.36-1.74)

14

10

41,636

Neomycin Sulfate

1.24 (0.52-2.97)

2

8

98,786

Nepafenac

1.12 (0.47-2.67)

5

5

130,145

Nevirapine

0.91 (0.35-2.36)

2

1

11,093

Niacin

1.19 (0.56-2.56)

15

18

562,443

Niacin/Simvastatin

1.02 (0.43-2.43)

5

5

67,992

Nicotine

0.71 (0.38-1.32)

53

35

118,598

Nicotine Polacrilex

0.70 (0.29-1.69)

6

3

7,728

Nifedipine

1.01 (0.49-2.06)

25

22

490,162

Nisoldipine

1.20 (0.45-3.19)

1

0

41,165

Nitazoxanide

1.05 (0.43-2.60)

2

4

36,038

Nitrofurantoin

1.15 (0.43-3.08)

1

0

29,132

Nitrofurantoin Monohydrate/Nitrofurantoin, Macro

0.88 (0.64-1.21)

296

264

2,246,357

Nitrofurantoin, Macrocrystals

0.92 (0.65-1.32)

219

207

1,536,408

Nitroglycerin

1.20 (0.68-2.12)

53

72

875,334

Nizatidine

1.15 (0.47-2.81)

3

4

93,943

Norethindrone

1.33 (0.64-2.75)

17

29

663,818

Norethindrone Acetate

1.08 (0.52-2.22)

19

26

195,889

Norethindrone;Placebo

1.31 (0.56-3.07)

4

10

224,396

Nortriptyline Hydrochloride

1.04 (0.66-1.63)

114

130

495,803

Nutritional Supplement

0.72 (0.28-1.81)

3

2

3,373

Nystatin

1.06 (0.71-1.57)

163

177

2,384,353

Nystatin/Triamcinolone Acetonide

1.00 (0.57-1.76)

64

62

1,208,860

Octreotide Acetate

0.96 (0.34-2.67)

1

0

5,528

Ofloxacin

1.05 (0.62-1.78)

74

77

1,568,642

Olanzapine

0.51 (0.41-0.63)

924

479

209,942

Olmesartan Medoxomil

1.01 (0.48-2.14)

20

15

481,143

Olopatadine Hydrochloride

1.18 (0.68-2.04)

62

75

1,872,773

Omalizumab

1.10 (0.41-2.91)

0

2

16,054

Omega-3-Acid Ethyl Esters

0.99 (0.51-1.91)

35

34

457,857

Omeprazole

0.93 (0.75-1.16)

689

659

4,583,291

Omeprazole/Sodium Bicarbonate

1.15 (0.49-2.71)

4

8

99,979

OnabotulinumtoxinA

0.98 (0.39-2.44)

2

3

20,683

Ondansetron

1.15 (0.94-1.39)

772

916

4,296,721

Orlistat

1.11 (0.46-2.68)

2

7

48,643

Orphenadrine Citrate

1.07 (0.59-1.92)

49

61

338,219

Oseltamivir Phosphate

1.33 (0.90-1.97)

145

205

3,856,503

Ospemifene

0.92 (0.36-2.38)

2

1

11,808

Oxaprozin

1.34 (0.62-2.89)

10

25

273,863

Oxazepam

0.73 (0.37-1.42)

37

29

47,995

Oxcarbazepine

0.52 (0.40-0.68)

608

319

237,391

Oxiconazole Nitrate

1.11 (0.48-2.59)

7

7

177,802

Oxybutynin Chloride

1.01 (0.55-1.84)

48

51

489,787

Oxycodone Hydrochloride

1.03 (0.79-1.35)

393

425

1,467,728

Oxymorphone Hydrochloride

0.96 (0.47-1.98)

20

28

67,549

Paliperidone

0.50 (0.29-0.88)

91

46

19,622

Paliperidone Palmitate

0.48 (0.21-1.06)

16

8

1,941

Pantoprazole Sodium

0.66 (0.51-0.86)

571

379

2,303,161

Paricalcitol

1.07 (0.40-2.86)

0

2

13,448

Paroxetine Hydrochloride

0.92 (0.74-1.15)

659

630

1,494,954

Paroxetine Mesylate

0.77 (0.34-1.79)

8

7

17,127

Pegfilgrastim

1.16 (0.42-3.15)

0

1

18,172

Peginterferon Alfa-2A

0.95 (0.39-2.27)

4

5

30,859

Penciclovir

1.20 (0.54-2.71)

8

14

218,197

Penicillin V Potassium

1.03 (0.77-1.38)

335

354

4,670,054

Pentosan Polysulfate Sodium

0.98 (0.44-2.19)

10

13

77,753

Pentoxifylline

1.17 (0.46-2.99)

1

2

46,307

Perindopril Erbumine

1.14 (0.43-3.01)

0

2

21,296

Permethrin

0.93 (0.57-1.52)

98

94

696,958

Perphenazine

0.54 (0.30-0.96)

81

47

16,150

Phenazopyridine Hydrochloride

1.01 (0.75-1.36)

320

333

2,301,705

Phendimetrazine Tartrate

1.16 (0.44-3.06)

0

2

25,036

Phenelzine Sulfate

0.63 (0.27-1.48)

7

6

3,698

Phenobarbital

0.71 (0.39-1.29)

58

45

52,650

Phentermine Hydrochloride

1.39 (0.68-2.84)

16

37

363,426

Phentermine Hydrochloride/Topiramate

1.02 (0.39-2.70)

1

1

14,176

Phenyleph HCl/Promethazine HCl

0.99 (0.44-2.23)

12

9

189,440

Phenytoin

0.89 (0.36-2.18)

3

4

15,937

Phenytoin Sodium, Extended

0.72 (0.39-1.31)

60

40

160,213

Phytonadione

0.93 (0.40-2.18)

6

7

39,805

Pilocarpine Hydrochloride

0.94 (0.39-2.28)

5

2

44,956

Pimecrolimus

1.39 (0.61-3.15)

7

13

545,792

Pimozide

0.84 (0.31-2.25)

2

0

4,636

Pindolol

0.82 (0.34-2.00)

4

3

12,345

Pioglitazone Hydrochloride

1.44 (0.69-2.98)

15

32

679,629

Piroxicam

1.11 (0.54-2.32)

19

23

378,776

Pitavastatin Calcium

1.06 (0.43-2.62)

3

2

51,810

Pneumococcal Vaccine Polyvalent

1.01 (0.43-2.37)

5

7

54,536

Podofilox

1.35 (0.58-3.15)

1

15

93,544

Polyethylene Glycol 3350

0.78 (0.52-1.19)

171

131

1,126,519

Polymyxin B Sulfate/Trimethoprim Sulfate

1.03 (0.60-1.77)

70

71

1,452,575

Potassium Chloride

0.79 (0.56-1.11)

270

212

1,734,415

Potassium Citrate

0.99 (0.43-2.24)

9

9

97,254

Potassium Nitrate/Sodium Fluoride

1.08 (0.46-2.53)

5

8

83,444

Pramipexole Dihydrochloride

0.95 (0.51-1.76)

43

46

199,824

Pramlintide Acetate

1.15 (0.44-2.97)

0

3

27,062

Prasugrel Hydrochloride

0.97 (0.41-2.32)

6

3

71,694

Pravastatin Sodium

0.94 (0.56-1.57)

87

77

1,683,042

Prazosin Hydrochloride

0.44 (0.31-0.63)

343

153

45,432

Prednisolone

1.00 (0.57-1.75)

65

59

1,923,387

Prednisolone Acetate/Sulfacetamide Sodium

1.19 (0.48-2.96)

2

3

84,863

Prednisolone Sodium Phosphate

1.40 (0.67-2.92)

18

25

2,002,828

Prednisone

1.33 (1.10-1.61)

737

1,013

10,667,620

Pregabalin

0.93 (0.64-1.34)

198

192

767,217

Prenatal Vitamins

1.06 (0.49-2.29)

17

14

485,963

Primidone

1.10 (0.50-2.43)

7

20

49,491

Prochlorperazine

1.05 (0.48-2.28)

12

17

121,555

Prochlorperazine Maleate

1.07 (0.67-1.70)

103

120

697,832

Progesterone

1.09 (0.57-2.10)

35

38

810,592

Progesterone, Micronized

0.85 (0.40-1.83)

21

10

260,195

Progesterone, Wettable

1.02 (0.37-2.80)

1

0

10,764

Promethazine Hydrochloride

1.29 (1.05-1.58)

632

846

5,356,893

Propafenone Hydrochloride

1.29 (0.48-3.44)

0

1

45,143

Propranolol Hydrochloride

0.65 (0.50-0.84)

563

372

862,028

Propylthiouracil

1.19 (0.45-3.16)

1

0

37,682

Protriptyline Hydrochloride

0.72 (0.31-1.67)

8

7

10,466

Pseudoephedrine Hydrochloride

1.10 (0.41-2.96)

1

0

19,816

Pyridostigmine Bromide

1.07 (0.41-2.82)

1

1

21,371

Quetiapine Fumarate

0.47 (0.41-0.53)

3,219

1,541

653,394

Quinapril Hydrochloride

1.05 (0.48-2.33)

13

11

290,364

Quinine Sulfate

1.20 (0.51-2.87)

3

8

107,313

Rabeprazole Sodium

1.45 (0.70-3.02)

14

32

616,990

Raloxifene Hydrochloride

1.46 (0.59-3.62)

1

4

240,525

Raltegravir Potassium

0.85 (0.35-2.04)

5

4

20,573

Ramelteon

0.73 (0.43-1.23)

92

70

135,619

Ramipril

1.09 (0.51-2.33)

18

16

590,504

Ranitidine Hydrochloride

0.97 (0.67-1.40)

202

200

2,020,604

Ranolazine

0.92 (0.38-2.25)

5

1

39,108

Repaglinide

1.06 (0.42-2.66)

3

1

52,210

Ribavirin

0.90 (0.38-2.10)

7

5

45,553

Rifampin

1.08 (0.49-2.35)

12

17

152,042

Rifaximin

0.87 (0.40-1.92)

15

10

109,125

Riluzole

0.93 (0.33-2.62)

1

0

4,250

Risedronate Sodium

1.44 (0.62-3.34)

4

12

380,336

Risperidone

0.49 (0.41-0.59)

1,470

741

396,965

Ritonavir

0.97 (0.42-2.26)

5

9

35,952

Rivaroxaban

1.03 (0.48-2.20)

15

20

132,732

Rivastigmine

0.74 (0.30-1.85)

4

1

6,126

Rizatriptan Benzoate

1.37 (0.81-2.31)

62

106

583,539

Roflumilast

0.89 (0.34-2.37)

2

0

7,774

Ropinirole Hydrochloride

0.71 (0.41-1.21)

88

58

286,422

Rosuvastatin Calcium

1.38 (0.77-2.45)

47

74

1,684,436

Rotigotine

0.98 (0.36-2.64)

0

2

6,023

Rufinamide

0.89 (0.31-2.55)

1

0

2,565

Salicylic Acid

1.09 (0.47-2.54)

7

7

157,189

Salmeterol Xinafoate

1.18 (0.49-2.86)

3

5

107,698

Salsalate

0.98 (0.41-2.35)

5

3

55,712

Saxagliptin Hydrochloride

1.08 (0.45-2.64)

4

3

85,338

Scopolamine

0.96 (0.50-1.83)

41

35

743,188

Selegiline

0.78 (0.36-1.72)

11

16

11,777

Selenium Sulfide

0.88 (0.40-1.91)

18

9

216,728

Sertraline Hydrochloride

0.61 (0.55-0.69)

3,126

1,961

3,480,351

Sevelamer Carbonate

1.01 (0.40-2.55)

2

2

25,227

Sildenafil Citrate

1.20 (0.65-2.23)

40

51

1,166,044

Silodosin

1.29 (0.48-3.44)

0

1

44,775

Silver Sulfadiazine

0.89 (0.57-1.40)

123

112

721,253

Simeprevir

0.94 (0.32-2.75)

0

1

2,209

Simvastatin

1.16 (0.81-1.67)

191

229

4,365,895

Sinecatechins

1.00 (0.38-2.61)

2

0

19,006

Sirolimus

1.06 (0.39-2.88)

1

0

14,434

Sitagliptin Phosphate

1.04 (0.50-2.15)

22

21

426,941

Sodium Bicarbonate

0.96 (0.36-2.55)

1

1

8,447

Sodium Chloride

0.88 (0.40-1.94)

15

9

129,009

Sodium Fluoride

1.14 (0.57-2.25)

29

31

1,037,839

Sodium Oxybate

0.96 (0.36-2.56)

1

1

8,825

Sodium Polystyrene Sulfonate

1.05 (0.42-2.62)

2

3

35,417

Sofosbuvir

0.99 (0.37-2.67)

0

2

6,738

Solifenacin Succinate

1.13 (0.54-2.35)

17

25

233,921

Somatropin, E-Coli Derived

1.13 (0.44-2.89)

1

2

35,622

Sotalol Hydrochloride

1.23 (0.48-3.15)

1

2

68,240

Spacer, Inhalation

1.23 (0.60-2.49)

21

31

535,076

Spinosad

1.00 (0.36-2.75)

1

0

8,399

Spironolactone

0.90 (0.53-1.53)

80

70

818,721

Sucralfate

1.08 (0.72-1.64)

139

164

707,040

Sulfacetamide Sodium

0.78 (0.43-1.42)

64

40

873,026

Sulfacetamide Sodium/Sulfur

1.20 (0.60-2.41)

23

33

491,388

Sulfamethoxazole/Trimethoprim

0.90 (0.76-1.07)

1,169

1,079

9,216,004

Sulfasalazine

1.20 (0.52-2.76)

5

12

129,332

Sulindac

1.00 (0.47-2.13)

17

17

203,430

Sumatriptan

0.85 (0.38-1.89)

14

8

92,758

Sumatriptan Succinate

1.21 (0.86-1.70)

213

278

1,393,060

Tacrolimus

1.31 (0.58-2.98)

7

13

361,820

Tadalafil

1.41 (0.69-2.88)

18

35

765,269

Tafluprost

0.92 (0.33-2.60)

1

0

3,796

Tamoxifen Citrate

1.09 (0.46-2.55)

7

5

177,268

Tamsulosin Hydrochloride

0.96 (0.60-1.54)

108

105

1,187,108

Tapentadol Hydrochloride

1.00 (0.53-1.90)

35

44

143,494

Tazarotene

1.08 (0.53-2.21)

22

25

375,700

Tdap Vaccine

1.20 (0.48-3.02)

2

2

87,643

Telmisartan

1.23 (0.50-2.99)

3

4

144,428

Temazepam

0.83 (0.65-1.06)

553

479

737,752

Temozolomide

1.00 (0.40-2.48)

1

5

17,163

Tenofovir Disoproxil Fumarate

1.17 (0.44-3.08)

0

2

26,212

Terazosin Hydrochloride

1.01 (0.45-2.28)

11

9

180,126

Terbinafine Hydrochloride

1.11 (0.57-2.16)

32

33

1,036,721

Terconazole

0.90 (0.53-1.52)

83

71

983,192

Teriparatide

1.01 (0.41-2.53)

2

3

27,337

Testosterone

1.25 (0.66-2.38)

32

49

622,093

Testosterone Cypionate

1.10 (0.52-2.30)

17

23

229,603

Testosterone Enanthate

0.88 (0.35-2.22)

4

0

20,599

Testosterone, Micronized

1.15 (0.47-2.80)

2

6

65,312

Tetracycline Hydrochloride

0.91 (0.48-1.74)

41

33

541,196

Theophylline

0.99 (0.43-2.32)

7

6

85,060

Thioctic Acid

0.95 (0.33-2.76)

0

1

2,473

Thioridazine Hydrochloride

0.59 (0.26-1.32)

13

8

5,299

Thiothixene

0.63 (0.29-1.35)

18

15

7,297

Thyroid

0.94 (0.48-1.84)

33

29

358,761

Thyroid Porcine

1.03 (0.38-2.81)

1

0

11,106

Tiagabine Hydrochloride

0.63 (0.31-1.29)

31

18

29,840

Ticagrelor

0.94 (0.37-2.43)

2

1

14,146

Timolol

1.28 (0.55-2.99)

4

10

184,278

Tinidazole

1.17 (0.55-2.49)

12

24

139,494

Tiotropium Bromide

1.16 (0.60-2.23)

30

44

326,533

Tizanidine Hydrochloride

1.12 (0.77-1.63)

174

210

916,645

Tobramycin

0.97 (0.58-1.64)

81

77

1,338,009

Tofacitinib Citrate

0.86 (0.32-2.35)

1

1

3,523

Tolterodine Tartrate

1.03 (0.50-2.11)

23

23

365,802

Topiramate

0.79 (0.62-1.01)

571

464

1,174,419

Torsemide

0.97 (0.43-2.20)

10

10

99,135

Tramadol Hydrochloride

1.10 (0.91-1.33)

832

948

4,673,715

Trandolapril

1.19 (0.45-3.16)

1

0

37,874

Tranexamic Acid

1.09 (0.45-2.66)

3

4

63,011

Tranylcypromine Sulfate

0.62 (0.26-1.45)

7

6

3,276

Travoprost

1.17 (0.49-2.79)

4

6

128,659

Trazodone Hydrochloride

0.39 (0.35-0.43)

4,727

1,856

1,918,471

Tretinoin

1.11 (0.74-1.69)

137

162

1,449,215

Triamcinolone Acetonide

1.20 (0.89-1.62)

285

354

5,620,180

Triamterene

0.97 (0.35-2.69)

1

0

6,202

Triazolam

0.89 (0.50-1.57)

62

56

345,105

Trifluoperazine Hydrochloride

0.68 (0.29-1.55)

8

9

5,357

Trifluridine

1.19 (0.46-3.11)

1

1

48,282

Trihexyphenidyl Hydrochloride

0.59 (0.28-1.24)

26

13

17,427

Trimethobenzamide Hydrochloride

0.80 (0.37-1.69)

21

13

99,698

Trimethoprim

0.99 (0.42-2.34)

5

6

50,410

Trospium Chloride

1.01 (0.41-2.46)

3

4

36,239

Typhoid Vaccine, Live

1.20 (0.48-2.99)

2

3

90,071

Urea

1.32 (0.57-3.03)

6

11

351,873

Ursodiol

0.99 (0.43-2.27)

9

7

119,526

Valacyclovir Hydrochloride

1.28 (0.91-1.82)

199

272

3,049,177

Valganciclovir Hydrochloride

1.17 (0.44-3.07)

0

2

26,098

Valproic Acid

0.58 (0.31-1.11)

52

29

32,314

Valsartan

0.77 (0.41-1.45)

54

30

823,092

Vancomycin Hydrochloride

0.71 (0.33-1.53)

21

10

62,112

Vardenafil Hydrochloride

1.27 (0.55-2.91)

7

10

360,349

Varenicline

1.38 (0.84-2.28)

71

117

943,582

Varicella Virus Vaccine

1.23 (0.55-2.73)

9

15

283,126

Venlafaxine Hydrochloride

0.64 (0.55-0.76)

1,578

1,039

1,805,783

Verapamil Hydrochloride

1.08 (0.59-1.98)

44

52

527,939

Vilazodone Hydrochloride

0.69 (0.42-1.13)

108

78

92,261

Vitamin B Complex and Vitamin C

1.04 (0.40-2.67)

1

2

19,057

Voriconazole

1.09 (0.41-2.90)

0

2

15,395

Vortioxetine Hydrobromide

0.54 (0.26-1.13)

29

12

14,493

Warfarin Sodium

0.80 (0.51-1.24)

145

113

944,887

Water, Sterile

1.03 (0.38-2.82)

1

0

11,771

Zafirlukast

1.19 (0.46-3.03)

1

2

51,315

Zaleplon

0.85 (0.51-1.39)

96

87

230,415

Ziprasidone Hydrochloride

0.67 (0.52-0.86)

565

397

122,623

Zolmitriptan

1.18 (0.57-2.43)

17

30

198,910

Zolpidem Tartrate

0.90 (0.79-1.03)

1,763

1,632

4,277,362

Zonisamide

0.95 (0.47-1.89)

26

31

101,424


Disclosure Statement

This research was supported by NIH grant R01 MH080122, AHRQ (CERT) grant U18HS016973, and the United States (US) Department of Veterans Affairs Center of Excellence for Suicide Prevention and Office of Mental Health and Suicide Prevention. The contents do not represent the views of the US Department of Veterans Affairs or the United States Government. Correspondence concerning this article should be sent to Robert D. Gibbons, Center for Health Statistics, University of Chicago, 5841 S. Maryland Ave., Room W260, MC2000 | Chicago, IL 60637, Office: 773-834-8692 | Email: [email protected]

All data used in this study were obtained from Truven Health as a part of their MarketScan database under license to the University of Chicago. The study was supported by NIH grant R01 MH080122, AHRQ (CERT) grant U18HS016973. Robert Gibbons has served as an expert witness in cases related to suicide for the US Department of Justice, and Pfizer, Wyeth, and GSK pharmaceutical companies and founded the company Adaptive Testing Technologies that distributes computerized adaptive mental health tests. These activities have been reviewed and approved by the University of Chicago in accordance with its conflict of interest policies. This study was reviewed and deemed exempt from review by the University of Chicago institutional review board.


©2019 Robert Gibbons, Kwan Hur, Jill Lavigne, Jiebiao Wang, and J. John Mann. This supplement is licensed under a Creative Commons Attribution (CC BY 4.0) International license, except where otherwise indicated with respect to particular material included in the supplement.

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